Dr. Richard Isaacson was featured by CNN discussing new research showing that better cardiorespiratory fitness in midlife may significantly reduce the risk of developing dementia, including Alzheimer’s disease. The study found that people with higher levels of aerobic fitness had better cognitive function, a lower long-term risk of dementia, and even delayed the onset of the disease—benefits that were especially pronounced among individuals with a genetic predisposition to Alzheimer’s.

Dr. Isaacson emphasized that while genetics play a role, lifestyle choices remain powerful tools for protecting brain health. As he noted, “There is a saying — genes are not our destiny; we can all make proactive choices to help win the tug-of-war against our genes. This study wholly supports that.” He also highlighted aerobic exercise as one part of a comprehensive brain-healthy lifestyle that includes proper nutrition, managing cardiovascular risk factors, prioritizing sleep, and regular preventive care.

Read the full CNN article to learn how improving aerobic fitness may help protect long-term brain health and reduce the risk of dementia.